COMPARISON OF BONE MARROW ASPIRATION INTERPRETATION WITH IMMUNOPHENOTYPING IN CHILDREN'S LEUKEMIA DIAGNOSIS

Prevalensi kanker pada anak semakin meningkat. Terdapat 90 pasien leukemia yang dirawat di RS Wahidin Sudirohusodo selama tahun 2013-2017. Diagnosis morfologi akut dibagi menjadi ALL dan AML kadang-kadang tidak sesuai dengan diagnosis flow cytometry, menunjukkan karakteristik sel ganas. Penelitian ini bertujuan untuk membandingkan hasil interpretasi aspirasi sumsum tulang imunofenotip dalam mendiagnosis anak. Metode Data dari rekam medis digunakan studi kohort retrospektif (usia 1–18 tahun) RS. Makassar 2013 hingga 2017. Semua kerja diperiksa tulangnya, diikuti oleh immunophenotyping, masing-masing kelompok dianalisis. Hasil Dari total subjek penelitian, akhir berdasarkan imunofenotipe adalah 60 30 usia rata-rata 8 3 bulan. Rasio laki-laki perempuan 1,7:1 (p = 0,353). Usia 7 10 bulan, AML, 9 0,409). Kesesuaian cytometry terhadap berturut-turut 92,3% 50%. Sebagian besar penanda berada CD 20 sensitivitas 100%, 117 92%. Kesimpulan kasus 50% AML. Hal penting penilaian garis keturunan definitif serta deteksi dini leukemia.Kata kunci: leukemia; anak; Immunophenotyping. ABSTRACT The prevalence of cancer in children is increasing. There were patients treated at hospital during the years 2013–2017. morphological acute divided into and sometimes incompatible with which shows characteristics malignant cells. This study aims to compare results interpretation bone marrow aspiration immunophenotyping diagnosing childhood leukemia. Methods from medical records was used a retrospective cohort (ages years) admitted Dr. All working examined for aspiration, followed by each group analyzed. Results Of subjects, final based on mean age months. male female ratio 1.7:1 0.353). months, 0.409). suitability morphology 92.3% 50%, respectively. Most markers groups sensitivity 100% each, Conclusion Morphological cases cases. important lineage assessment definitive as well early detection